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Muddy Brown Granular Casts three ways - Brightfield, Darkfield, Phase Contrast.

Dr. Vipin Varghese @vipvargh

#Muddy #Brown #Granular
Muddy Brown Granular ... Varghese @vipvargh #Muddy ... Granular #Casts #clinical ... #urine #microscopy
Granular & “Muddy Brown” Casts on Urine Microscopy
A. Finely granular cast B. slightly coarser granular cast
Granular & “Muddy ... Brown” Casts on Urine ... “urine poker quads ... coarse (c) and muddy ... #Microscopy #Clinical
Examples of varying granular and granular/waxy mixed casts: 
A: coarse granular/broad-waxy (and surrounding white blood cells);
light granular/muddy ... granular, C and D: muddy ... MuddyBrown #Casts #Urine ... #Microscopy #Clinical
Muddy Brown Casts in ATN
#Clinical #Path #Nephro #Urine #Microscopy #MuddyBrownCasts #ATN
Muddy Brown Casts ... in ATN #Clinical ... #Path #Nephro #Urine
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
Nephritic vs Nephrotic Syndrome ... nephrotic/nephritic syndromes ... dysmorphic RBCs in urine ... Nephritic #Nephrotic #Syndrome
Urine Microscopy - Casts
Acellular Casts
 • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
Urine Microscopy ... • "Muddy Brown ... suggestive of nephrotic sydnrome ... EricsMedicalLectures/ #Casts #Urine
Urinary Casts and Disease Associations
Hyaline - May be nonspecific; seen in normal individuals or during severe
and concentrated urine ... cellular casts "Muddy-brown ... Fatty - Nephrotic syndrome
Causes Abnormal Urine Color - Differential Diagnosis
Turbid White Urine (Albinuria):
 • Chyluria, Filariasis, Schistosomiasis, Malignancy, Phosphaturia,
Causes Abnormal Urine ... • Drummond's syndrome ... (blue diaper syndrome ... Bag Syndrome - ... Myoglobinuria, Nutcracker syndrome
Purple Urine Bag Syndrome
Chronic, indwelling catheter + bacteriuria (Providencia, Klebsiella, E.coli*) + alkaline urine
Tryptophan → Indoxyl
Purple Urine Bag ... Syndrome Chronic ... E.coli*) + alkaline urine ... #Bag #Syndrome ... pathophysiology #clinical
Metabolic Pathways of Purple Urine Bag Syndrome: Adopted from chart originally published in Purple Urine Bag
Pathways of Purple Urine ... Bag Syndrome: Adopted ... published in Purple Urine ... Bag Syndrome: A ... #Bag #Syndrome