6 results
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
lymphoproliferative disorder ... • Symptoms of anemia ... • hemolytic anemia ... Positive Coombs testing ... Symptoms: High fevers
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Agglutination - Cold ... bartonella (oroya fever ... Consider RBC membrane disorder ... workup #hematology #testing
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Nail Disorders secondary ... Diseases Nail Fold ... Iron deficiency anemia ... growth (e.g.. shock ... Differential #Diagnosis #Algorithm
Chest Pain Diagnosis and Management Algorithm
STEMI:
 - Hx: Pressure like CP, Radiation to arm/jaw, CAD risk
and Management Algorithm ... onset, severe, tearing ... underlying dz (SLE, uremia ... friction rub, Fever ... , Dyspnea, H/O COPD
Evaluation of suspected incomplete Kawasaki Disease

1. AHA consensus recommendations
2. Infants ≤6 months old on day ≥7
Infants ≤6 months old ... on day ≥7 of fever ... should undergo lab testing ... Albumin ≤3.0 g/dL, anemia ... within 10 d of fever
PFAPA Syndrome - Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Adenitis

EPIDEMIOLOGY:
PFAPA is the most common syndrome entailing
detected with testing ... PFAPA syndrome, lasting ... - Familial cold ... neonatal-onset multisystem ... contributor to this disorder