5 results
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
AIHA Primary Secondary ... Secondary Cold ... Positive Coombs testing ... younger pts) Differential ... Symptoms: High fevers
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Diagnosis Algorithm ... Agglutination - Cold ... bartonella (oroya fever ... Consider RBC membrane disorder ... workup #hematology #testing
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Nail Disorders secondary ... Diseases Nail Fold ... growth (e.g.. shock ... #dermatology #Differential ... #Diagnosis #Algorithm
Causes of Secondary Amenorrhea - Differential Diagnosis Algorithm
Absence of menses for more than 3 cycles or
Causes of Secondary ... Amenorrhea - Differential ... Diagnosis Algorithm ... failure (<35 years old ... disorder, weight
PFAPA Syndrome - Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Adenitis

EPIDEMIOLOGY:
PFAPA is the most common syndrome entailing
DIFFERENTIAL DIAGNOSIS ... detected with testing ... - Familial cold ... neonatal-onset multisystem ... contributor to this disorder