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Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
Clinical Picture ... variable degree of weakness ... Limb- proximal weakness ... Diagnosis - Clinical ... Clinical DX: -
Myasthenia Gravis - Summary • an autoimmune disease of the postsynaptic neuromuscular junction associated with antibodies
Diagnosis: • Based on clinical ... or respiratory weakness ... mild to moderate weakness ... or generalized weakness ... - Improves clinical
Ocular Myasthenia Gravis on Physical Exam A 41yo female was referred by her neurologist for double vision.
Ocular Myasthenia ... Her clinical exam ... non-localized EOM weakness ... Myasthenia gravis ... #PhysicalExam #clinical
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 Floppy Baby Syndrome • Infantile Botulism • Acute Flaccid Myelitis • Guillain Barre • Neonatal Myasthenia
Barre • Neonatal Myasthenia ... Gravis Clinical ... resistance - Weakness
Ptosis - Differential Diagnosis Framework Ptosis (Greek- to fall) Drooping of the upper eyelid that usually results
think about three clinical ... Myasthenia gravis ... to ptosis and weakness ... Horner syndrome • Myasthenia ... Myotonic dystrophy • Myasthenia
Statin Induced Muscle Toxicity - Summary Clinical Presentation: • Elevations of serum creatine kinase with proximal myalgia
Toxicity - Summary Clinical ... proximal myalgia and weakness ... symmetric muscle weakness ... Lambert-Eaton myasthenic ... IU/I • SAMS clinical
Myasthenia Gravis - Ptosis, Diplopia, Blurred Vision Acute Myasthenic Crisis • Triggered by infection, medication • Respiratory
Myasthenia Gravis ... Vision Acute Myasthenic ... ventilation #Myasthenia
Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm No Objective Weakness • Cardio-pulmonary disease
of Peripheral Weakness ... No Objective Weakness ... Oculomotor • Myasthenia ... Lambert-Eaton Myasthenic ... #Peripheral #Weakness
Drugs associated with worsening of Myasthenia Gravis (MG): • D-penicillamine • Botulinum toxin. • Telithromycin • Fluoroquinolones • Quinine • Magnesium • Macrolide antibiotics • Corticosteroids (may cause transient
with worsening of Myasthenia ... prevent prolonged myasthenic ... higher risk of myasthenic ... because of bulbar weakness
Diagnosis of Myasthenia Gravis - Physical Exam Maneuvers • Sustained lateral gaze for seconds to elicit
Diagnosis of Myasthenia ... due to laryngeal weakness ... for neck flexor weakness ... fatigable limb weakness ... BrighamMedRes #Myasthenia
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