43 results
Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm
No Objective Weakness
 • Cardio-pulmonary disease
Cardio-pulmonary disease ... • Endocrine Disease ... Oculomotor • Myasthenia ... Lambert-Eaton Myasthenic ... Syndrome • Botulism
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
variable degree of weakness ... Limb- proximal weakness ... syndrome - Miller ... Severe bulbar weakness ... Gravis #diagnosis #management
Graves Hyperthyroidism - Diagnosis and Management Algorithm
Low TSH -> TSH-R-Ab+ -> Graves' Hyperthyroidism

doi: 10.1210/clinem/dgaa646

#Graves #Disease #Hyperthyroidism
Graves Hyperthyroidism ... Diagnosis and Management ... dgaa646 #Graves #Disease ... #Management #Algorithm ... treatment #diagnosis #endocrinology
Causes of Proximal Muscle Weakness That May Mimic Inflammatory Myopathy
 • Central or peripheral neurologic disease
Proximal Muscle Weakness ... peripheral neurologic disease ... • Myasthenia ... Trichinosis - Lyme disease ... - Hypo- or hyperthyroidism
Graves' Disease Treatment
Thionamides (mainly methimazole)
 • Chance of remission in up to 2 years
 • No
Graves' Disease ... mendesthiagob #Graves #Disease ... #Treatment #Management ... #endocrinology ... #hyperthyroidism
Hypothyroidism – symptoms and signs.

Symptoms: 
Tiredness/malaise, 
Weight gain,
Anorexia,
Cold intolerance, 
Poor memory,
Change in appearance, 
Depression, 
Poor libido,
Hypothyroidism – ... Myalgia, Muscle weakness ... of movement, Deafness ... Carpal timel syndrome ... #PhysicalExam #Endocrinology
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Neuromuscular Weakness ... Demyelinating Disease ... Guillain-Barre syndrome ... Lambert Eaton Syndrome ... , Myasthenia Gravis
Myasthenia Gravis - Summary
 • an autoimmune disease of the postsynaptic neuromuscular junction associated with antibodies
an autoimmune disease ... or respiratory weakness ... mild to moderate weakness ... or generalized weakness ... Gravis #diagnosis #management
Hashitoxicosis - Autoimmune thyroid disease overlap syndrome of Graves' and Hashimoto's disease

Autoimmune thyroid disease overlap syndrome
overlap syndrome ... overlap syndrome ... → Hypothyroidism ... → Hypothyroidism ... Hashitoxicosis #Endocrinology
Hirsutism & Virilization - Differential Diagnosis Algorithm
ADRENAL EXCESS
Ovarian
 • Polycystic Ovarian Syndrome
 • Hyperthecosis
 • Tumor
Adrenal
Polycystic Ovarian Syndrome ... • Cushing's Syndrome ... Obesity • Liver Disease ... Medical/Other • Hypothyroidism ... Diagnosis #Algorithm #endocrinology