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Table of Causes of Acute Liver Injury
#Diagnosis #Hepatology #Acute #Liver #Injury #Causes #Differential #Incidence #Table #Failure
Table of Causes of Acute ... Liver Injury #Diagnosis ... #Hepatology #Acute ... #Liver #Injury ... #Causes #Differential
Clinical manifestations of acute liver failure 

Brain: 
Hepatic encephalopathy,  
Cerebral edema,  
Intracranial hypertension,
Coagulopathy, Lactic ... acidosis Systemic ... Subclinical myocardial injury ... lung injury, ... Signs #Symptoms #Diagnosis
Causes of Severe Acute Liver Injury
 - Ichemic hepatitis
 - Acute biliary obstruction
 - Drug-Induced liver
Liver Injury ... - Drug-Induced liver ... injury - Viral ... #Causes #Differential ... #Hepatology #Diagnosis
Stroke Mimics - Differential Diagnosis - MINT Mnemonic
 • Metabolic: Hyper-glycemia, Hypoglycemia, Wernicke's encephalopathy, Mitochondrial Encephalopathy
Stroke Mimics - Differential ... Diagnosis - MINT ... Encephalopathy with Lactic ... Acidosis and Stroke-like ... Traumatic Brain Injury
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... - Differential ... Diagnosis Algorithm ... Liver Injury: ... #hepatology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Tests (LFTs) - Differential ... Diagnosis Framework ... Hepatopathy • Acute ... injury) • Ischemic ... #Diagnosis #hepatology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Liver Injury - Differential ... Diagnosis Hepatocellular ... #Injury #Differential ... #Diagnosis #Causes ... #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
ALT: ↑ • GGT/5-NT ... nucleotidase (5-NT ... #chemistry #diagnosis ... #differential # ... Hepatology #transaminitis
Workup for Hyperphosphatemia - Differential Diagnosis Framework
Rule out spurious hyperphosphatemia: paraproteinemia, hyperlipidemia, hemolysis, hyperbilirubinemia, liposomal amphotericin
Hyperphosphatemia - Differential ... Diagnosis Framework ... t-PA, heparin Acute ... Transcellular Shift: • Lactic ... acidosis, DKA
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
Metformin Associated Lactic ... Acidosis (MALA) ... cycle found in the liver ... gastrointestinal distress and acute ... kidney injury are