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diagnosis management oncology rheumatology chronic druginduced hemeonc hemophagocytic hlh lymphohistiocytosis sle syndrome aclf acute cell cirrhosis classification comparison dil erythematosus
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Drug Induced Lupus ... vs SLE Drug Induced ... Epidemiology: -10% of all ... to 1:1 F:M • Clinical ... • Immunologic Workup
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
incompetent • CLL ... Orange or Hep C Clinical ... microglobulin Treatment ... Leukemia #diagnosis #workup ... #oncology #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... SJIA], systemic lupus ... Sepsis • Drug-induced ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Failure (ACLF) Clinical ... in those with CLD ... months without treatment ... Hepatitis (AAH) Drug-Induced ... Failure #Cirrhosis #Hepatology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook Presentation: • Plts ↓50% (nadir
Heparin Induced ... complex → plt activation ... Diagnosis: • Clinical ... Diagnosis #Management #Treatment ... #Hematology #HemeOnc
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... lymphoproliferative syndrome Clinical ... extremities Drug Induced ... Antihistone: Drug induced ... activation and/
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... excessive macrophage activation ... Low or absent NK cell ... • Bicytopenia Treatment ... #hematology
When to look for clonal/neoplastic hypereosinophilia (HEo)? - Exclusion of frequent causes (Drug-induced HEo, helminthiasis, cancer,
frequent causes (Drug-induced ... ) - Clinical symptoms ... Cytopenia, Other cell ... Diagnosis #Signs #Hematology ... #Workup
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... factor (GCSF) treatments ... unclassifiable: Reduced ... Workup: • Complete ... Syndromes #diagnosis #hematology
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
Drug Induced Lupus ... Epidemiology: -10% of all ... to 1:1 F:M • Clinical ... • Immunologic Workup ... #DIL #rheumatology
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