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differential management infections activetb infectiousdiseases latenttb neurology syndrome aids cd4 cns differentiation evaluation hematology hiv hivaids inflammatory iris manifestations mycobacteria
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
mycobacterial infection (NTM ... rest LTBI (-) Immune ... Diagnosis: Latent ... and Culture • CXR ... #TB #Diagnosis
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
mycobacterial infection (NTM ... rest LTBI (-) Immune ... Diagnosis: Latent ... and Culture • CXR ... #TB #Diagnosis
Neurological Manifestations of Tuberculosis Spinal Arachnoiditis & Polyradiculopathy: • Subacute onset of limb weakness, bladder/bowel dysfunction, muscle
TB • Many possible ... Imaging: cerebral edema ... due to increased CSF ... #diagnosis #differential ... #TB #neurology
Pulmonary Infections in HIV-AIDS Bacterial: • No organism identified, Strep pneumoniae, H. influenzae, S.aureus, Streptococcus Grp
, NTM (M.kansasii ... embolism, Pulm edema ... Fungal, AFB), TB ... Infections #HIVAIDS #workup ... #diagnosis #evaluation
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... myalgias, HoTN, edema ... common • Imaging: CXR ... - pulmonary opacities ... sepsis), PE, DAH, CHF
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
belonging to the Mycobacterium ... tuberculosis complex ... massiliense in CF ... Kansasii: • Mimics TB ... Diagnosis Of NTM
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
, pulmonary infiltrates ... fevers • MAC/NTM ... organizing PNA • Mycobacterium ... leukoencephalopathy (PML ... and peripheral edema
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
Antimicrobial treatment ... required until immune ... + mass effect/Edema ... - Hemorrhage, tuberculomas ... - +mass effect/Edema
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