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diagnosis oncology algorithm allergy bandemia basophils chronic immunology leukemoidreaction lymphocytic management markers neutrophil neutrophils pathergy pathophysiology skin wbc workup
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
Blood Disorders ... (CLL) - CD38(new ... CD23, o CML ... bcr-able (+) ↑ WBC ... #Disorders #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
• (Peripheral eosinophilia ... Neutrophils • Immature/Myeloblasts ... Age: 50-60 • Auer ... lymphoma #Leukemia ... #Hematology #Oncology
Evaluation of Leukocytosis: The term 'leukocyte' applies to any cells within the myeloblast, monoblast, & lymphoid lineages. Include
cells within the myeloblast ... , monoblast, & lymphoid ... cell (WBC) count ... Mature WBC: 80- ... LEUCOCYTOSIS WBC
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Lymphocytosis on CBC ... lymphoproliferative disorders ... leukemia, Hodgkin ... leukemia #CLL ... workup #oncology #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Autoimmune disorders ... : • Full Blood ... platelets - WBC ... Immunohistochemical studies (to differentiate ... #hematology #oncology
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
on the left Myeloblast ... Tissue damage • Leukemia ... Even with normal WBC ... 21% had normal WBC ... #CBC #hematology
Pathergy Summary Overview What is pathergy? Pathergy is an exaggerated skin injury occurring after minor trauma such as
Chronic myeloid leukemia ... (CML) treated with ... syndrome • Non-Hodgkin's ... lymphoma What ... allergy #immunology #dermatology
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