7 results
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Diagnosis Algorithm Blood ... Decreased RBC ... Infiltration Increased RBC ... Thalassemia • RBC ... • RBC Metabolism
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell ( ... disease, McLeod blood ... Unstable hemoglobin disorders ... #Morphology #differential ... diagnosis #hematology #microscopy
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Algorithm Normal Blood ... Smear • Drugs ... Neutrophils - Low RBC ... • Small Bowel Disorder ... Cells, Normal WBCs
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential ... decreased PLT count: CBC ... plateletcount), peripheral blood ... changes), high MCV anemia ... disease), HBsAg/anti-HBc
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Immunoglobulin M (IgM) • Blood ... smear - RBC agglutination ... younger pts) Differential ... sensitize red blood ... cells (RBCs) at
Borrelia recurrentis on Peripheral Blood Smear
23M Somali refugee recently arrived w/severe abd pain, confusion and fever
on Peripheral Blood ... Smear 23M Somali ... Hgb 12.5, WBC 14 ... recurrentis #BloodSmear #microscopy ... #pathology #clinical
Fever After International Travel

Infectious Disease:
• Endemic in either the destination or home region

Viral Syndromes:
Arboviral infections, a
No hemolytic anemia ... Investigations: • CBC ... a chest film; blood-smear ... dipstick test, microscopic ... Fever #Travel #Differential