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diagnosis algorithm abnormal bandemia causes chronic classification disorders hemolysis hemolytic hodgkins lfts liver lymphocytic lymphoma management mds myelodysplasia myelodysplastic neutrophil
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Fragmentation - MAHA: TTP ... 2) External (RBC ... 3) Internal (RBC ... , Spiders - Enzyme ... #Diagnosis #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
deficiency, Other enzyme ... thrombocytopenia - DIC, TTP ... hypertension • Unusual RBC ... acanthocytes - Consider RBC ... #hematology #testing
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... Lymphocytosis on CBC ... • Neutropenia, anemia ... #diagnosis #workup ... #oncology #hematology
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Even with normal WBC ... relative to both WBC ... bacteremia • Abnormal WBC ... diagnosis #neutrophil #WBC ... #CBC #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
decreased PLT count: CBC ... smear, HIV/HCV testing ... changes), high MCV anemia ... ), HBsAg/anti-HBc ... #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory ... value for this enzyme ... hallmark for the disease ... from ischemia WBC ... #Hematology
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
metabolic syndrome criteria ... decision for repeat testing ... body mass index; FBC ... Abnormal #Algorithm #Hepatology ... #Differential #
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
cell count (anemia ... Myeloproliferative Disease ... differential • ... Syndromes #diagnosis #hematology ... #oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma - Clinical ... Hodgkin Lymphoma Workup ... platelets - WBC ... classification #hematology ... #oncology #management
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