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hemolytic agglutinin algorithm atlas causes classification cold hodgkins intravascular lymphoma management mds microscopy monoclonal morphology myelodysplasia myelodysplastic nomenclature paraproteinemias rbc
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
anemia): ... ) (e.g. lupus, CLL ... #Causes #differential ... #diagnosis #hematology ... #anemia
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Unstable hemoglobin disorders ... hemolytic anemia ... hemolytic anemia ... #Red #BloodCell ... #diagnosis #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
• Symptoms of anemia ... Diagnosis: • hemolytic ... anemia • Cold ... #hemolytic #anemia ... #hematology #diagnosis
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Consider RBC membrane disorder ... elliptocytosis, autoimmune ... #Anemia #Differential ... #workup #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
count (anemia) ... • Aplastic Anemia ... Megaloblastic Anemia ... Myelophthisic Anemia ... #hematology #oncology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Lymphoma (HCV) • CLL ... et diutinum Neurologic ... anemia due to cold ... Paraproteinemias #Hematology ... #Diagnosis #Oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
disorders Hodgkin ... Weight loss • Anemia ... anemia • Pain ... Hodgkin Lymphoma Workup ... classification #hematology
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