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leukemia chronic abscess agglutinin arteritis b12 classification cobalamin cold cvid deficiency erythematosus gap gca giantcell globulin hemeonc hemolytic hodgkins hospitalization
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... Neutrophils • Immature/Myeloblasts ... - infiltrates (anemia ... #Leukemia #Hematology ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
: • Most common ... Orange or Hep C Clinical ... • Neutropenia, anemia ... #workup #oncology ... #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
immunophenotype Clinical ... 5) Symptoms of anemia ... marrow failure with anemia ... #Leukemia #oncology ... #diagnosis #management
Fatigue and IBD Algorithm • 40-50% patients have fatigue despite clinical remission • Risk factors: BMI,
Fatigue and IBD ... , Anemia • Prevalence ... Crohn's > UC Anemia ... #IBD #Algorithm ... #diagnosis #management
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
• Symptoms of anemia ... include fatigue ... anemia • Cold ... #hemolytic #anemia ... #hematology #diagnosis
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... Granulomatous lymphocytic ... autoimmune hemolytic anemia ... DDX - Other causes ... #diagnosis #management
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
count (anemia) ... : Macrocytic anemia ... Anemia • Bone ... Megaloblastic Anemia ... #hematology #oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... Immune hemolytic anemia ... (NSHL) - (most common ... Hodgkin Lymphoma Workup ... #oncology #management
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
• Common Causes ... autoantibodies (pernicious anemia ... Worsening macrocytic anemia ... wt loss • If anemia ... - CBC, PBS - anemia
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
infection • Most common ... Lung Abscess - Clinical ... night sweats, fatigue ... Leukocytosis, anemia ... #causes #management
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