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diagnosis oncology management leukemia differential lupus lymphocytic sle arthritis atlas bloodcell cellulitis classification common comparison cvid dermatology disorders druginduced erythematosus
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
, Chronic disease ... , MDS, Chemotherapy ... myeloma Rouleaux: Chronic ... differential #diagnosis #hematology ... #microscopy #atlas
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... -> AML: Blast crises ... Neutrophils • Immature/Myeloblasts ... - infiltrates (anemia ... #Leukemia #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... Infection exposure (l MD ... PT, aPTT(liver disease ... not required in all ... #Workup #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Orange or Hep C Clinical ... cells can indicate disease ... Leukemia #diagnosis #workup ... #oncology #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... Leukemia (CLL) ... immunophenotype Clinical ... chemotherapy for low-risk disease ... Leukemia #oncology #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Marrow Failure • Chronic ... Myeloproliferative Disease ... Workup: • Complete ... Syndromes #diagnosis #hematology
Vibrio Vulnificus skin infection Cirrhosis w/recent consumption of raw oysters w/rapidly evolving rash. Vibrio vulnificus part of
marine microbiota & causes ... All oysters at Chesapeake ... liver disease, ... immunosuppressive meds ... #legs #clinical
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to impaired B-cell ... to 8 years Clinical ... Autoimmunity • Chronic ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Epidemiology: -10% of all ... to 1:1 F:M • Clinical ... • Evolution: Chronic ... disease Dr. ... comparison #table #rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... polarized light microscopy ... • Serum and urine ... ANA and RF (if clinical ... diagnosis #testing #Rheumatology
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