10 results
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
lymphoproliferative disorder ... infection, autoimmune disorder ... Positive Coombs testing ... post infectious setting ... Monoclonal IgM Includes Disorders
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Consider RBC membrane disorder ... #Anemia #Differential ... Diagnosis #Algorithm #workup ... #hematology #testing
Pulmonary Hypertension Groups - WHO Classification
Group I - Vascular remodeling of pulmonary arteries
 • Idiopathic, HIV,
connective tissue disorders ... Sarcoidosis, chronic hemolytic ... anemia, thyroid ... disorders, sickle ... Symptoms of right
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... smear, HIV/HCV testing ... pylori test (GI symptoms ... changes), high MCV anemia ... Diagnosis #Causes #Workup
Dysphagia - Differential Diagnosis Framework

Symptom | Diagnosis
• Solid-food dysphagia present for months to years | Mechanical
Diagnosis Framework Symptom ... URGENT WORKUP ... Esophageal Dysphagia: Testing ... Diagnosis #Management #gastroenterology ... #workup
Irritable Bowel Syndrome (IBS) - Diagnosis and Workup Summary
Use a positive diagnostic strategy with minimal testing.
Diagnosis and Workup ... strategy with minimal testing ... last 3 months + symptom ... Pelvic Floor Disorder ... #gastroenterology
Gastroesophageal Reflux Disease (GERD) - Summary

GERD: Diagnosis
• Heartburn (substernal burning sensation) and acid regurgitation
• Chest pain
Extraesophageal
cough GERD: Testing ... weeks GERD - Testing ... EGD Impedance testing ... exclude motility disorders ... diagnosis #management #Gastroenterology
Scurvy (Vitamin C Deficiency) - Diagnosis and Management

Vitamin C is required for hydroxylation of proline residues
disorders • Selective ... autism spectrum disorder ... musculoskeletal symptoms ... Psychiatric symptoms ... contribute to nonimmune hemolysis
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Autoimmune disorders ... nodosum • Immune hemolytic ... ingestion • B symptoms ... -95% of cases) Classification ... Hodgkin Lymphoma Workup
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... formed or don’t work ... age 70 years Symptoms ... Neutropenia • Platelet Disorders ... Workup: • Complete