Pulmonary Hypertension Groups - WHO Classification Group I - Vascular remodeling of pulmonary arteries • Idiopathic, HIV, connective tissue disorders Group II - Left-sided heart disease causing back up of blood flow • Left heart failure, aortic valve disease, mitral valve disease Group III - Chronic lung disease causing hypoxemia • COPD, ILD, sleep apnea Group IV - CTEPH • Pulmonary Embolism Group V - Unclear and multifactorial • Sarcoidosis, chronic hemolytic anemia, thyroid disorders, sickle cell anemia, splenectomy, mediastinal tumors, chronic renal failure on hemodialysis WHO PH Functional Classification I - No limitation of usual physical activity II - No issues at rest, but normal activity worsens dyspnea, fatigue, or chest pain. III - No issues at rest, but normal activity is markedly limited by dyspnea, fatigue, chest pain, or pre-syncope. IV - Unable to perform activity at rest. Symptoms of right ventricular failure might be present at rest. - Dr. Rishi Kumar @rishikumarmd #Pulmonary #Hypertension #PHTN #Groups #WHO #Classification #diagnosis
