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diagnosis hematology anemia differential disease management nephrology nephrotic oncology agglutinin algorithm ascorbicacid causes cold glomerulonephritis groups hodgkins hypertension initial lymphoma
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
lymphoproliferative disorder ... infection, autoimmune disorder ... Positive Coombs testing ... post infectious setting ... Monoclonal IgM Includes Disorders
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Consider RBC membrane disorder ... #Anemia #Differential ... Diagnosis #Algorithm #workup ... #hematology #testing
Recommended initial testing for patients being evaluated for glomerular disease 24-hour urine collection - Quantify proteinuria.
Recommended initial testing ... LDH - Assess for hemolysis ... C4 - Test for disorders ... for autoimmune disorders ... #testing #workup
Pulmonary Hypertension Groups - WHO Classification Group I - Vascular remodeling of pulmonary arteries • Idiopathic, HIV,
connective tissue disorders ... Sarcoidosis, chronic hemolytic ... anemia, thyroid ... disorders, sickle ... Symptoms of right
Recommended initial testing for patients being evaluated for glomerular disease 1) 24-hour urine collection - Quantify proteinuria.
Recommended initial testing ... LDH - Assess for hemolysis ... C4 - Test for disorders ... #workup #diagnosis ... #initial #testing
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... smear, HIV/HCV testing ... pylori test (GI symptoms ... changes), high MCV anemia ... Diagnosis #Causes #Workup
Scurvy (Vitamin C Deficiency) - Diagnosis and Management Vitamin C is required for hydroxylation of proline residues
disorders • Selective ... autism spectrum disorder ... musculoskeletal symptoms ... Psychiatric symptoms ... contribute to nonimmune hemolysis
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Autoimmune disorders ... nodosum • Immune hemolytic ... ingestion • B symptoms ... -95% of cases) Classification ... Hodgkin Lymphoma Workup
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... formed or don’t work ... age 70 years Symptoms ... Neutropenia • Platelet Disorders ... Workup: • Complete
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