17 results
Anaphylaxis: Pathogenesis
Anaphylaxis is a Type 1 hypersensitivity reaction
While the primary mechanism of anaphylaxis is mast cell
Anaphylaxis: Pathogenesis ... Anaphylaxis is ... cell activation, basophils ... #Anaphylaxis ... pathophysiology #immunology
Type I Hypersensitivity: Pathogenesis and clinical findings
Definition: Production of lgE Antibodies that bind to harmless allergens
leading to an allergic ... Sensitization" to Allergen ... Initial exposure to allergen ... conjunctivitis • Anaphylaxis ... #Immunology #pathophysiology
Drug Treatment of Anaphylaxis and Allergic Reactions
First-Line Therapy 
 - Epinephrine 
 - Oxygen 
 -
Drug Treatment of Anaphylaxis ... and Allergic Reactions ... Prednisone #Anaphylaxis ... #Management #Pharmacology ... #Medications #Allergy
Anaphylaxis: Signs and Symptoms
Anaphylaxis: when any egg of three conditions is met:
1. Acute onset of skin/mucosal
Anaphylaxis: Signs ... and Symptoms Anaphylaxis ... exposure to a likely allergen ... exposure to known allergen ... pathophysiology #immunology
Management of Anaphylaxis - Interventions
Epinephrine - Bolus, Infusion, Nebulized
Posture
O2
Fluids
Albuterol 
H1-Antihistamines, H2-Antihistamines
Glucocorticoids
Additional Vasopressor
Glucagon
Sugammadex
Methylene blue
Tranexamic acid
ECMO

#anaphylaxis #management #treatment
Management of Anaphylaxis ... Tranexamic acid ECMO #anaphylaxis ... #management #treatment ... Interventions #allergy
Anaphylaxis: Treatments (Acute)
Additional Info:
 • IV steroids may be considered for prevention of late phase reactions.
Anaphylaxis: Treatments ... provided, as well as allergy ... Ventolin inhaler #Anaphylaxis ... #Treatments #Management ... pathophysiology #immunology
Algorithm for Suspected Penicillin Allergy in Patients Undergoing Surgery 

• Cephalosporins may be prescribed to patients
Suspected Penicillin Allergy ... reported penicillin allergy ... 100,000 risk of anaphylaxis ... #Penicillin #Allergy ... #Preoperative #Management
Penicillin Allergy Pathway for Antibiotic Prescription in Patients With Penicillin Allergy
Mild Reaction - Itching, Minor rash
Penicillin Allergy ... With Penicillin Allergy ... HSR), EMR lists allergy ... lgE-Mediated) HSR - Anaphylaxis ... Prescription #algorithm #management
IDSA Surgical Wound Infection Algorithm
Algorithm for the management and treatment of surgical site infections (SSIs). 
*For
Algorithm for the management ... patients with type 1 (anaphylaxis ... or hives) allergy ... Algorithm #IDSA #management
Antibiotics for severe community-onset pneumonia 

Atypical coverage always 

- Usually azithromycin 500 mg daily 

- Doxycycline
anaphylactic penicillin allergy ... of penicillin anaphylaxis ... Antibiotics #Coverage #Management