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diagnosis management cardiology differential endocarditis hematology algorithm amiodarone bands common cvid diseases hypogammaglobulinemia ild immunodeficiency induced infectiousdiseases interstitial leucocytosis leukemia
Causes of Interstitial Lung Disease - Differential Diagnosis Algorithm Idiopathic Interstitial Pneumonia • (UIP) Usual Interstitial Pneumonia
Causes of Interstitial ... Lung Disease - ... Metastases to lung ... Hypersensitivity Pneumonia - Immunologic ... Diseases #ILD #Causes
Evaluation of Leukocytosis: The term 'leukocyte' applies to any cells within the myeloblast, monoblast, & lymphoid lineages. Include
cells within the myeloblast ... eosinophils, & basophils ... the underlying cause ... NEUTROPHILS #WCC #BASOPHILS
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
• Chronic lung ... lymphocytic interstitial lung ... DDX - Other causes ... hypogammaglobulinemia #immunology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... eosinophilia, basophilia ... Neutrophils • Immature/Myeloblasts
Endocarditis Summary Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV substance use • IV catheter • Recent
verrucous) • Lung ... positive in 90% of IE cases ... • Petechiae Immunologic ... Septic Emboli Cause ... Treat underlying cause
Amiodarone Induced Lung Toxicity Summary Who? • 5% of patients • Dose ≥ 400 mg per day How? Possible
Amiodarone Induced Lung ... Direct cytotoxic lung ... hypersensitivity/immunologic ... Exclude other causes ... Amiodarone #Induced #Lung
Endocarditis - Overview and Differential Diagnosis Framework Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV
, verrucous) - Lung ... positive in 90% of IE cases ... • Petechiae Immunologic ... Septic emboli cause ... Treat underlying cause
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