12 results
Evaluation of Leukocytosis:
The term 'leukocyte' applies to any cells within the myeloblast, monoblast, & lymphoid lineages.
Include
cells within the myeloblast ... eosinophils, & basophils ... the underlying cause ... NEUTROPHILS #WCC #BASOPHILS
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Diagnosis and Management ... Cytopenia: Common • Immunologic ... Positive in 60-80% of cases ... Usual therapeutic management ... Erythematosus #Diagnosis #Management
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
drug-dependent) • Immunologic ... Discontinuation of causal ... Cytopenia: Common • Immunologic ... Usual therapeutic management ... rheumatology #diagnosis #management
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
and M panel Management ... DDX - Other causes ... hypogammaglobulinemia #immunology ... hematology #diagnosis #management
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... eosinophilia, basophilia ... Neutrophils • Immature/Myeloblasts
Endocarditis Summary

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV substance use
• IV catheter
• Recent
positive in 90% of IE cases ... • Petechiae Immunologic ... Septic Emboli Cause ... Treat underlying cause ... Endocarditis #diagnosis #management
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
muscles: “myasthenic crises ... first step in immunologic ... Myasthenia Crises ... Gravis #diagnosis #management
The algorithm below shows how pre-test probability could be combined with various criteria to determine which
acyclovir in these cases ... HSV PCR would cause ... chemistries and immunologic ... is proposed: #Management
Amiodarone Induced Lung Toxicity Summary

Who?
• 5% of patients
• Dose ≥ 400 mg per day

How?  Possible
hypersensitivity/immunologic ... pulmonary nodules and masses ... Exclude other causes ... • Favorable in case ... Pulmonary #diagnosis #management
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Virologic and immunologic ... unintentional weight loss, nausea ... Differential #Diagnosis #Management