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Here are very large, immature myeloblasts with many nucleoli. A distincitve feature of these blasts is
large, immature myeloblasts ... #Clinical #Path ... #BloodSmear #Blood
Elliptocyte - 
Note the shape of these appropriately named erythrocytes.
In addition to hereditary elliptocytosis, elliptocytes can
megaloblastic anemia ... myelophthisic anemia ... sideroblastic anemia ... #Clinical #Path ... #BloodSmear #Blood
Dacrocytes (tear drop cells) 
Other poikilocytes resemble a pear or teardrop. The narrow, tapered end
may be
metaplasia, pernicious anemia ... some hemolytic anemias ... #Clinical #Path ... #BloodSmear #Blood
Here is another peripheral blood smear demonstrating changes with iron deficiency anemia. Note the increased zone
iron deficiency anemia ... #Clinical #Path ... PeripheralBloodSmear #BloodSmear ... #Anemia #IronDeficiency
Codocytes (Target cells) - Two target cells are seen in the left photo and one in
with hemolytic anemias ... #Clinical #Path ... #BloodSmear #Blood
Schistocytes - The arrows point to schistocytes which are fragmented red blood cells. Also called schizocytes,
seen in hemolytic anemias ... microangiopathic hemolytic anemia ... Clinical conditions ... #Clinical #Path ... #BloodSmear #Blood
A – cabot ring, B – Howell-Jolly Body

What are Cabot’s rings?
- They are delicate threadlike inclusions
/megaloblastic anaemia ... #Clinical #Pathology ... #Microscopy #BloodSmear
Summary of types of haemolytic anaemia. Visit gramproject.com for more medical diagrams, tables and flowcharts for
of haemolytic anaemia ... #diagnosis #clinical ... #management #differential ... #algorithm #anaemia
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Bandemia Overview ... Normal: < 1% Clinically ... on the left Myeloblast ... Degree of bandemia ... likelihood of negative clinical
Multiple Myeloma Diagnosis and Management Summary
Clinical Signs:
 • hyperCalcemia 28% (bone demineralization)
 • Renal disease 48%
Diagnosis and Management ... Summary Clinical ... hypercalcemia) • Anemia ... plus one of: • Anemia ... Myeloma #Diagnosis #Management