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diagnosis anemia differential hemolytic causes intravascular cold disease testing workup
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
usually IgM) (e.g. primary ... cold agglutin disease ... • Intrinsic RBC ... #Hemolytic #Intravascular ... differential #diagnosis #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Diagnosis Algorithm ... Cold AIHA • Alloimmune ... elliptocytosis - RBC ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
15% of AIHA Primary ... Viral infection, autoimmune ... Blood smear - RBC ... CLL (older) • Autoimmune ... #anemia #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Differential Diagnosis Algorithm ... Agglutination - Cold agglutinins ... elliptocytosis, autoimmune ... Differential #Diagnosis #Algorithm ... #workup #hematology
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