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diagnosis anemia causes differential hemolytic intravascular agglutinin algorithm disease
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
(AIHA)"Cold" (usually ... IgM) (e.g. primary ... • Intrinsic RBC ... #Hemolytic #Intravascular ... differential #diagnosis #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Warm AIHA • Cold ... AIHA • Alloimmune ... elliptocytosis - RBC ... Complement-Mediated • Cold ... Algorithm #Causes #Hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
15% of AIHA Primary ... Viral infection, autoimmune ... Blood smear - RBC ... CLL (older) • Autoimmune ... #anemia #hematology
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