7 results
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Causes Intravascular ... e.g. lupus, CLL, lymphoma ... usually IgM) (e.g. primary ... • Intrinsic RBC ... #diagnosis #hematology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Algorithm Vascular Causes ... Celiac disease • Autoimmune ... : Autoimmune hepatitis ... cell lung CA, lymphoma ... diagnosis #algorithm #hepatology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
15% of AIHA Primary ... disorder or lymphoid ... - Monoclonal - Lymphoid ... Blood smear - RBC ... #anemia #hematology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
nodosum • Immune hemolytic ... platelets - WBC ... Treatment • Early ... classification #hematology ... #oncology #management
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
assessment+++ Primary ... solid cancers • Autoimmune ... Treatment: • ... Lymphohistiocytosis #diagnosis #management ... #rheumatology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... biliary cirrhosis ... Nephrogenic DI Hematologic ... Adenocarcinoma Treatment ... #Diagnosis #Management
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
: • Treat primary ... cause • Correct ... hydration • RBC ... #treatment #management ... #hematology