7 results
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
, lymphoma, idiopathic ... usually IgM) (e.g. primary ... • Intrinsic RBC ... #Causes #differential ... #diagnosis #hematology
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
spherocytosis, Autoimmune ... : Cold autoimmune ... Malignant lymphoma ... #Morphology #differential ... #diagnosis #hematology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Liver Injury - Differential ... • Autoimmune: ... , HLH • Neoplasm ... lung CA, lymphoma ... diagnosis #algorithm #hepatology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
assessment+++ Primary ... lymphoma, B-cell ... solid cancers • Autoimmune ... Lymphohistiocytosis #diagnosis #management ... #rheumatology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
15% of AIHA Primary ... disorder or lymphoid ... Blood smear - RBC ... pts) Differential ... #hematology #diagnosis
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Chronic Lymphocytic ... lymphoma (Richter ... chemotherapy for low-risk disease ... Leukemia #oncology #hematology ... hemeonc #diagnosis #management
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
nodosum • Immune hemolytic ... platelets - WBC ... Treatment • Early ... classification #hematology ... #oncology #management