7 results
diagnosis anemia causes hemolytic intravascular oncology agglutinin chronic classification cold dic differential disseminated hemophagocytic hlh hodgkins leukemia lymphocytic lymphohistiocytosis sjogrens
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
coagulation (DIC ... , lymphoma, idiopathic ... usually IgM) (e.g. primary ... • Intrinsic RBC ... differential #diagnosis #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
15% of AIHA Primary ... disorder or lymphoid ... - Monoclonal - Lymphoid ... Blood smear - RBC ... #hematology #diagnosis
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
lymphoma (Richter ... chemotherapy for low-risk disease ... Leukemia #oncology #hematology ... #hemeonc #diagnosis ... #management
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
• Severe Liver Disease ... : • Treat primary ... hydration • RBC ... #causes #treatment ... #management #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
assessment+++ Primary ... lymphoma, B-cell ... solid cancers • Autoimmune ... Lymphohistiocytosis #diagnosis #management ... #rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
biliary cirrhosis ... Nephrogenic DI Hematologic ... • B cell lymphoma ... Sjogrens #Syndrome #Rheumatology ... #Diagnosis #Management
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
nodosum • Immune hemolytic ... platelets - WBC ... Treatment • Early ... classification #hematology ... #oncology #management
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