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diagnosis algorithm differential liver pbc primary acute causes cirrhosis aih anemia aplastic dili druginduced liverinjury oncology pathophysiology pruritus severe workup
Causes of Severe Acute Liver Injury - Ichemic hepatitis - Acute biliary obstruction - Drug-Induced liver
Severe Acute Liver Injury ... - Acute biliary ... - Autoimmune ... cholangitis ... #Differential #Hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
: Autoimmune hepatitis ... • Bilirubin: RBC ... cardiac muscle, RBC ... • LDH: Heart, RBC ... diagnosis #algorithm #hepatology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
of Acute Liver Injury ... Other: NAFLD, Autoimmune ... biliary obstruction ... Malignancy, 1° PBC ... Acute #algorithm #hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Cirrhosis (PBC) ... - Summary PBC ... 30-65 years PBC ... Diagnosis: • Viral hepatitis ... #workup #hepatology
Primary Biliary Cirrhosis - Pathophysiology Environmental Risk Factors: Geographic location, Smoking, Microbial triggers, Xenobiotics, Nail polish Epigentics Risk
relative with PBC ... cell mediated autoimmune ... T-cell mediated BEC injury ... Cholestasis #PBC ... Pathophysiology #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
cholangitis, Primary ... sclerosing cholangitis ... steatosis • Autoimmune ... hepatitis #DILI ... Diagnosis #Algorithm #hepatology
Proposed Schema for the Management of Pruritus in Primary Biliary Cholangitis (PBC). Cholestyramine up to 4g
Schema for the Management ... Pruritus in Primary Biliary ... Cholangitis (PBC ... #Cholangitis #PBC ... #Management #Hepatology
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
Autoimmune Hepatitis ... pattern of liver injury ... reported (eg AIH-PBC ... (eg Viral) Management ... #Hepatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Marrow (Toxic injury ... Pancytopenia: • ↓ RBC ... • ↓ WBC • ↓ ... Anemia #oncology #hematology ... #diagnosis #management
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