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differential hematology management agglutinin ana anemia antibodies antinuclear cardiology causes cold disease erythematosus gap globulin hemolytic joint lupus monoarthritis monoarticular
Causes of Pericardial Effusion - Differential Diagnosis Infectious: • Viral: Enterovirus, Herpesvirus, Adenovirus, Parvovirus • Bacterial: Mycobacterium
of Pericardial Effusion ... - Differential Diagnosis ... Non-Infectious: • Rheumatologic ... SLE, Rheumatoid Arthritis ... • Malignant -
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Differential Diagnosis ... , erythema and WBC ... Rheumatologic Disease ... #Differential #Diagnosis ... #MSK #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
SLE), Sjogren's Syndrome ... , Sjögren Syndrome ... Non-Rheumatic Diseases: Malignancy ... ANA #patterns #rheumatology ... #diagnosis #differential
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... rheumatologic diseases ... Lungs: • Pleural effusions ... titers > 1:80 • CBC ... #Rheumatology
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Pulmonary Renal Syndromes ... OnePager Summary Autoimmune ... coagulopathy) • CBC ... o infection • Echocardiogram ... LVEF, pericardial effusion
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Viral infection, autoimmune ... disorder or lymphoid malignancy ... Blood smear - RBC ... CLL (older) • Autoimmune
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
be any age) Autoimmune ... thickening or effusion ... Arthralgia and Arthritis ... Malignancy Risk ... #Rheumatology #
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
RP-ILD), dermato-rheumatologic ... lung disease Malignancy ... dermatomyositis) Malignancy ... • Nonerosive arthritis ... Other Diseases: • PBC
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
changes (POEMS syndrome ... (RA, Temporal arteritis ... Cirrhosis, ETOH, autoimmune ... hepatitis, PBC, ... #differential #diagnosis
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