7 results
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Malaise, bleeding, infections ... pain, bleeding, infections ... Neutrophils • Immature/Myeloblasts ... bruising, bleeding, infection ... Hematology #Oncology #Diagnosis
Evaluation of Leukocytosis:
The term 'leukocyte' applies to any cells within the myeloblast, monoblast, & lymphoid lineages.
Include
cells within the myeloblast ... In adults, leukocytosis ... in peripheral blood ... solid tumors, and bacterial ... infections.
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
weeks without infection ... phenomenon CLL Diagnosis ... Lymphocytosis: Absolute blood ... Transform to DLBCL, PML ... #diagnosis #workup
Septic Arthritis: Pathogenesis and clinical findings
Notes:
- Septic Arthritis is typically monoarticular & the knee is involved
cases - decr blood ... Microbiology: - Bacterial ... infection is most ... gonorrhoeae in young adults ... pathophysiology #diagnosis
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Phagocytosis of blood ... Ferritin >1000 ng/ml ... sIL-2R >2400 Ul/ml ... CMV, HHV8,...), Bacteria ... diseases: SLE+++, Adult-onset
IDSA Recommendations for Preventing and Treating Varicella Zoster Virus (VZV) Infections in HIV-AIDS
Pre-Exposure Prevention of VZV
IDSA Recommendations ... Indications: • Adult ... health-care provider diagnosis ... , 2 doses (0.5 mL ... #HIVAIDS #pharmacology
IDSA Recommendations for Treating Mycobacterium Tuberculosis Infection and Disease in HIV-AIDS
Treating LTBI (to prevent TB disease)
Indications:
IDSA Recommendations ... and molecular diagnostic ... recommended for all ... recommendations and to the Adult ... #HIVAIDS #pharmacology