10 results
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... Neutrophils • Immature/Myeloblasts ... -> Invade Skin: ... #Hematology #Oncology ... #Diagnosis
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
- Pruritus: (focal ... involved) • No leukemic ... Malignancies (eg CML ... , ALL) • Solid ... hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Hepatomegaly • Skin ... microglobulin Treatment ... leukemia, Hodgkin ... #Leukemia #diagnosis ... workup #oncology #hematology
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm

DIFFUSE
Scarring - Irreversible-biopsy required
 • Lupus
and Focal) Differential ... Alopecia totalis (all ... Alopecia universalis (all ... #Focal #HairLoss ... #Alopecia #dermatology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Diagnosis Algorithm ... Hodgkin Lymphoma ... lymphadenopathy more diffuse ... Treated Like Acute Leukemias ... pathophysiology #Hematology
Allopecia - Differential Diagnosis Framework for Hair Loss

Localized / Focal Hair Loss Pattern:
 • Scarring Alopecia:
Diagnosis Framework ... Traction alopecia Diffuse ... weight loss • Chronic ... #Diagnosis #dermatology ... #Hairloss
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... permanent alopecia Differential ... with Lupus: • Chronic ... cyclophosphamide) • Hodgkin ... lymphoma and leukemia
Scleroderma Like Conditions - Differential Diagnosis
Eosinophilic Fasciitis:
 - Orange peel induration (peau d'orange) of proximal extremities
Like Conditions - Differential ... Diagnosis Eosinophilic ... the mainstay of treatment ... frequent in men Chronic ... #table #dermatology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
just beneath the skin ... involve one, two, or all ... Marrow Failure • Chronic ... (CML) • Felty ... #hematology #oncology
Pathergy Summary Overview

What is pathergy?
Pathergy is an exaggerated skin injury occurring after minor trauma such as
Sweet syndrome • Chronic ... myeloid leukemia ... (CML) treated with ... #differential # ... allergy #immunology #dermatology