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hematology oncology differential syndrome rheumatology algorithm causes chronic classification cll disorders hodgkins infectiousdiseases lymphocytic lymphoproliferative neurology workup 1 aids anemia
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
cells - Blood & BM ... • Cytopenia -> BM ... Neutrophils • Immature/Myeloblasts ... Age: 50-60 • Auer ... #Oncology #Diagnosis
A 37-year-old woman initially presented with pancytopenia and found to have leukopenia (2.1 × 103/μL) with
She was diagnosed ... promyelocytic leukemia ... a bone marrow (BM ... hospitalization and treatment ... acute myeloid leukemia
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 Hyperviscosity Syndrome - Causes and Treatment - Waldenstrom macroglobulinemia (most common) / Plasmapheresis - Multiple
Syndrome - Causes and Treatment ... hyperleukocytosis (AML ... - MH/CCF/CWRU EM ... #Differential #Diagnosis ... #Treatment #Management
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
the non-Hodgkin lymphoma ... phenomenon CLL Diagnosis ... microglobulin Treatment ... Transform to DLBCL, PML ... #diagnosis #workup
Tumor Lysis Syndrome An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
like Burkitt's lymphoma ... in high grade lymphoma ... & Acute leukemia ... malignancies Treatments ... TLS #oncology #management
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
- Differential Diagnosis ... Responsive to Treatment ... Treated Like Acute Leukemias ... growth, response to treatment ... relapse - Amy
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Immunosuppression (e.g., HIV), EBV ... involved) • No leukemic ... Differential Diagnosis ... , ALL) • Solid ... comparison #oncology #diagnosis
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
• Most common leukemia ... minimal tumor burden Diagnosis ... to large cell lymphoma ... hematology #hemeonc #diagnosis ... #management
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
accounts for 10% of all ... • History of EBV ... Treatment • Early ... #diagnosis #classification ... hematology #oncology #management
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
sIL-2R >2400 Ul/ml ... Hodgkin, T-cell lymphoma ... , B-cell lymphoma ... Unknown cause Treatment ... #management #treatment
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