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hematology oncology differential disorders hodgkins algorithm apl auerrods blood bloodsmear causes chronic clinical cll comparison hemophagocytic hlh hyperviscosity lymphocytic lymphohistiocytosis
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
cells - Blood & BM ... • Cytopenia -> BM ... Neutrophils • Immature/Myeloblasts ... Age: 50-60 • Auer ... #Oncology #Diagnosis
A 37-year-old woman initially presented with pancytopenia and found to have leukopenia (2.1 × 103/μL) with
She was diagnosed ... promyelocytic leukemia ... a bone marrow (BM ... hospitalization and treatment ... acute myeloid leukemia
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 Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphomas and Lymphoproliferative ... - Differential Diagnosis ... Treated Like Acute Leukemias ... relapse - Amy ... #Disorders #Classification
Hyperviscosity Syndrome - Causes and Treatment - Waldenstrom macroglobulinemia (most common) / Plasmapheresis - Multiple
Syndrome - Causes and Treatment ... hyperleukocytosis (AML ... - MH/CCF/CWRU EM ... #Differential #Diagnosis ... #Treatment #Management
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
phenomenon CLL Diagnosis ... and other C Cell lymphoproliferative ... microglobulin Treatment ... Transform to DLBCL, PML ... #diagnosis #workup
Post-Transplantation Lymphoproliferative Disorders (PTLD) Definition: Lymphoid and/or plasmacytic proliferations that occur as a result of immunosuppression in
PTLD) Definition: Lymphoid ... Epidemiology: Lymphoma ... accounts for 21% of all ... and classification ... #management #transplant
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Immunosuppression (e.g., HIV), EBV ... involved) • No leukemic ... translocation • Types: Classification ... Differential Diagnosis ... comparison #oncology #diagnosis
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
accounts for 10% of all ... • History of EBV ... Treatment • Early ... #diagnosis #classification ... hematology #oncology #management
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
sIL-2R >2400 Ul/ml ... Hodgkin, T-cell lymphoma ... , B-cell lymphoma ... Unknown cause Treatment ... #management #treatment
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