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oncology management anemia aplastic bruising coagulation dermatologic dic differential gpa granulomatosis hemostasis intravascular mds myelodysplasia myelodysplastic polyangiitis rash rheumatology syndromes
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... night sweats, bleeding ... Neutrophils • Immature/Myeloblasts ... #Hematology #Oncology ... #Diagnosis
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Disseminated Intravascular ... promyelocytic leukemia ... organ damage Clinical ... #Coagulation #diagnosis ... #management #hematology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Rarely dominate the clinical ... Polyarteritis nodosa • Microscopic ... Nasopharyngeal carcinoma ... Polyangiitis #GPA #dermatology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
- Differential Diagnosis ... gingivitis or gingival leukemic ... liver failure, disseminated ... discern these causes ... #Hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
unusual bruising or bleeding ... by bleeding (petechiae ... • Hairy Cell Leukemia ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia Clinical ... ecchymoses, mucosal bleeding ... and petechiae Causes ... virus (EBV) • Leukemia ... Anemia #oncology #hematology
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