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differential anemia causes coagulation defects deficiencies management mds myelodysplasia myelodysplastic platelet summary syndromes thrombocytopenia
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
- Differential Diagnosis ... Megakaryopoiesis • Aplastic ... Leukemia, Tumour ... Non-lmmune: • HELLP Syndrome ... #Hematology
Summary of Coagulation Deficiencies Inherited: • Hemophilia A - Deficiency of Factor VIII • Hemophilia B -
Deficiencies Inherited ... promyelocytic leukemia ... Deficiencies #Summary #table ... #comparison #diagnosis ... #hematology #deficiency
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
, CTLA4 deficiency ... thymoma DDX: • Inherited ... virus (EBV) • Leukemia ... #Anemia #oncology ... #hematology #diagnosis
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
basophilia, and thrombocytosis ... Neutrophils • Immature/Myeloblasts ... • Tumor lysis syndrome ... #Hematology #Oncology ... #Diagnosis
Inherited Qualitative Platelet Defects Bernard-Soulier Syndrome • Defect of adhesion due to a lack of GP Ib/IX/V
Inherited Qualitative ... a storage pool deficiency ... Platelet #Defects #comparison ... #table #differential ... #diagnosis #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Causes • Anemia • Aplastic ... • Hairy Cell Leukemia ... or folic acid deficiency ... #diagnosis #hematology ... #oncology
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