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hematology oncology differential algorithm generalized management pruritus systemic anemia aplastic myelodysplasia primary syndromes treatment
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... Secondary Thrombocytosis ... syndrome • Myelofibrosis ... Chronic myeloid leukemia ... #Causes #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic ... Syndrome (MD) - ... old, ~10,000 new cases ... transformation to acute leukemia ... #Syndrome #MDS
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Syndromes (MDS) ... DDX: Rule Out Secondary ... Chronic Myelogenous Leukemia ... • Hairy Cell Leukemia ... #Syndromes #diagnosis
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
• Lymphoma • Leukemia ... Throbocythemia • Myelodisplastic ... syndrome Psychiatric ... Pruritus #primary #secondary ... #generalized #dermatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
basophilia, and thrombocytosis ... Neutrophils • Immature/Myeloblasts ... • Tumor lysis syndrome ... bone marrow and secondary ... #Diagnosis
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
• Lymphoma • Leukemia ... syndrome Psychiatric ... #Pruritus #secondary ... #generalized #dermatology ... #Algorithm #causes
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... • Hypocellular myelodysplastic ... syndrome (MDS) ... virus (EBV) • Leukemia ... #diagnosis #management
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