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differential prolonged pt bleeding bruising dic disseminated hemochromatosis hemostasis intravascular microangiopathy thrombotic tma treatment
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
dysfunction (25%) • Hepatic ... deficiency) • HIT: Heparin-PF4 ... 100mg/dL) - Heparin ... #diagnosis #causes ... #hematology
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm Suspected TMA: Unexplained thrombocytopenia + MAHA
TMA: Unexplained thrombocytopenia ... hemoglobin/hemosiderin, Hepatic ... normal • DAT ... #Management #Algorithm ... #hematology
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... unfractionated heparin ... e.g. heparin ... #Causes #diagnosis ... #differential #hematology
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
(e.g. heparin contamination ... thrombin inhibitors, heparin ... #Causes #diagnosis ... #differential #hematology ... #coagulation
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
PT/ABNORMAL PTT ... Acquired: • Heparin ... PT/ABNORMAL PTT ... discern these causes ... #Hematology
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. Step 1: In the patient with
elevated iron indices ... including liver and hematologic ... hemochromatosis; HIC, hepatic ... #diagnosis #management ... #hepatology #gastroenterology
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