8 results
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
- Differential ... Diagnosis Algorithm ... • Placenta • Leukocytes ... biliary Cholangitis (PBC ... #hepatology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
• Blasts > 10% leukocytes ... , weight loss, abdominal ... Neutrophils • Immature/Myeloblasts ... #Leukemia #Hematology ... #Oncology #Diagnosis
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Pathophysiology ... Labs: • Alkaline ... obstruction • ALP ... bile ducts Differential ... #workup #hepatology
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
peripheral blood leukocytes ... on the left Myeloblast ... #Bandemia #differential ... #WBC #CBC #hematology ... #pathophysiology
Maculopapular - Diagnostic Algorithm
Pathophysiology:
- Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Maculopapular - Diagnostic ... : - Catch-all term ... #Dermatology #Rash ... Targetoid #Algorithm #Differential ... #Ddxof
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
) Pathophysiology ... nausea, vomiting, abdominal ... infiltration) Differential ... Diagnosis: Viral ... Liver #Pregnancy #hepatology
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
ALP, alkaline phosphatase ... ; ALT, alanine aminotransferase ... body mass index; FBC ... Abnormal #Algorithm #Hepatology ... Liver #Enzymes #Differential
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Incidence: common in APL ... ATRA treatment Pathophysiology ... if high risk if WBC ... initiation • Differential ... #management #hematology