8 results
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
) Elevation - Differential ... • Placenta • Leukocytes ... Cholangitis (PBC ... #Elevation #Differential ... #hepatology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Tests - Differential ... Diagnosis Algorithm ... or AST > ALP): ... stone, Biliary ... #hepatology #LiverFunctionTests
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Liver Injury - Differential ... Diagnosis Algorithm ... Bilirubin - +/- elevation ... #diagnosis #algorithm ... #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Bilirubin - +/- elevation ... normal AST/ALT ... liver #chemistry #diagnosis ... #differential # ... Hepatology #transaminitis
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
peripheral blood leukocytes ... on the left Myeloblast ... ) Differential ... #WBC #CBC #hematology ... #pathophysiology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Primary Biliary ... Pathophysiology ... obstruction • ALP ... bile ducts Differential ... #workup #hepatology
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
magnitude of enzyme elevation ... include extrahepatic biliary ... body mass index; FBC ... #Algorithm #Hepatology ... Liver #Enzymes #Differential
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Incidence: common in APL ... ATRA treatment Pathophysiology ... initiation • Differential ... 500 mg QD until normal ... #management #hematology