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apml bandemia basophils differentiation leucocytosis management neutrophils oncology syndrome wbc
Evaluation of Leukocytosis: The term 'leukocyte' applies to any cells within the myeloblast, monoblast, & lymphoid lineages. Include
white blood cell (WBC ... Mature WBC: 80- ... LEUCOCYTOSIS WBC ... Neutrophil bands ... #BANDS #NEUTROPHILS
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Band neutrophils ... peripheral blood leukocytes ... #diagnosis #neutrophil ... #WBC #CBC #hematology ... #pathophysiology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
ATRA treatment Pathophysiology ... if high risk if WBC ... acute febrile neutrophilic ... QD until normal WBC ... #management #hematology
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