9 results
Primary Adrenal Insufficiency
Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
aldosterone Causes ... of Adrenal Insufficiency ... sodium • ↑ Serum potassium ... Check sodium, potassium ... addisons #disease #endocrinology
Causes of Adrenal Insufficiency - Differential Diagnosis Algorithm
ACTH-Dependent (Secondary):
 • Pituitary Dysfunction
 • Hypothalamic Dysfunction
ACTH-Independent (Primary):
Causes of Adrenal ... Insufficiency - ... Polyglandular Autoimmune Syndrome ... #Insufficiency ... #endocrinology
Causes of Hypercalcemia
Parathyroid hormone–dependent
Primary hyperparathyroidism
Familial hypocalciuric hypercalcemia
Lithium-associated
Tertiary hyperparathyroidism
Genetic disorders (e.g., multiple endocrine neoplasia type 1 or
Causes of Hypercalcemia ... thyrotoxicosis, adrenal ... insufficiency ... Hypercalcemia #Causes ... Differential #Diagnosis #Endocrinology
Infectious Causes of Adrenal Insufficiency
Anatomical distribution of vessels to the adrenal makes the gland prone to
Infectious Causes ... of Adrenal Insufficiency ... Waterhouse-Friderichsen syndrome ... #Adrenal #Insufficiency ... differential #diagnosis #endocrinology
Adrenal Insufficiency - Diagnosis and Management Summary
Primary Adrenal Insufficiency:
Most Common Cause in the US: Autoimmune Adrenalitis
Other
Adrenal Insufficiency ... Most Common Cause ... Adrenal Insufficiency ... hypophysitis, Sheehan's syndrome ... Diagnosis #Management #Endocrinology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... Neutrophils • Immature/Myeloblasts ... develop leukostasis syndrome ... • Tumor lysis syndrome ... Intracellular Urate, Potassium
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
• Recent IV potassium ... - Tumor lysis syndrome ... insufficiency/Failure ... differential #diagnosis #causes ... #potassium #high
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
• Recent IV potassium ... - Tumor lysis syndrome ... insufficiency/Failure ... differential #diagnosis #causes ... #potassium #high
Causes of Hyperkalemia
l. Pseudohyperkalemia
  A Cellular efflux; thrombocytosis, erythrocytosis, leukocytosis, in vitro hemolysis
  B.
Causes of Hyperkalemia ... Advanced renal insufficiency ... insufficiency ... antiphospholipid syndrome ... Diagnosis #High #Potassium