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diagnosis clinical msk radiology algorithm disease management alkaline als amyotrophic bands basophils cardiology cardiomyopathy chronic deposition diarrhea elevation fibroma fracture
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... • Blasts > 10% leukocytes ... Splenomegaly • ↑ Leukocyte ... Neutrophils • Immature/Myeloblasts ... AML Dx: • ↑ Leukocyte
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
Alkaline Phosphatase (ALP ... ) Elevation - Differential ... Intestine - Other causes ... • Placenta • Leukocytes ... #Elevation #Differential
Evaluation of Leukocytosis: The term 'leukocyte' applies to any cells within the myeloblast, monoblast, & lymphoid lineages. Include
Leukocytosis: The term 'leukocyte ... cells within the myeloblast ... part automated differential ... precursor cells to leukocytes ... the underlying cause
Restrictive Cardiomyopathy - Diagnosis and Causes Clinical: Dyspnea, Exercise Intolerance, ↑ "Right Sided-Symptoms" (ascites, hepatomegaly, ↑↑peripheral edema) Physical
Diagnosis and Causes ... Echocardiography, Cardiac MRI ... : Amyloidosis (AL ... Cardiomyopathy #Diagnosis #Causes ... #differential #
Algorithm for the Evaluation of Chronic Diarrhea (< 7 days) Exclude: 1. Causes of acute diarrhea 2. Lactose intolerance 3.
Causes of acute ... disease - Fecal leukocytes ... barium, CT, or MR ... workup #diagnosis #differential
Osgood-Schlatter Disease - MSK Radiology Imaging Findings: • Infrapatellar fat-pad edema with loss of the patellar tendon
Case description ... DOES NOT OSD in all ... • MRI is more sensitive ... tibial tuberosity Differential ... patella #clinical #mri
Hydroxyapatite Deposition Disease (HADD) - MSK Radiology Imaging Findings: • Ovoid hypointense structures along the bursal surface
Case description ... • MRI shows globular ... low-signal on all ... Differential diagnosis ... Disease #clinical #mri
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
Lateral Sclerosis (ALS ... - Causes progressive ... Escorial criteria uses ... MRI: Brain, cervical ... conditions listed in differential
Haglund Syndrome - MSK Radiology Imaging Findings: • The Haglund Deformity (enlarged superior margin calcaneal posterior process)
Case description ... >1 mm AP, ... Differential diagnosis ... Heel #clinical #mri
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... Vasculitis Differential ... oligoclonal bands • MRI ... tract, and often causes ... , Elevated AST ALT
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