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oncology apml bandemia bands basophils cancer comparison cppd differentiation emergencies gout management neutrophil oncologic rheumatology syndrome wbc wcc
Evaluation of Leukocytosis: The term 'leukocyte' applies to any cells within the myeloblast, monoblast, & lymphoid lineages. Include
: The term 'leukocyte ... cells within the myeloblast ... LEUCOCYTOSIS WBC ... part automated differential ... #LEUCOCYTOSIS #LEUKEMOIDREACTION
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
peripheral blood leukocytes ... on the left Myeloblast ... #diagnosis #neutrophil ... #WBC #CBC #hematology ... #pathophysiology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
ATRA treatment Pathophysiology ... acute febrile neutrophilic ... : • Labs: leukocytosis ... initiation • Differential ... #management #hematology
Oncologic Emergencies - Differential Diagnosis Framework HEMATOLOGIC ONCOLOGIC EMERGENCIES: Hyperviscosity Syndrome: • Spontaneous bleeding • Shortness of breath
Emergencies - Differential ... Diagnosis Framework ... HEMATOLOGIC ... : • Absolute neutrophil ... Vomiting, decreased urine
CPPD vs Gout == CPPD == Think About CPPD When: • Self-limited synovitis after surgery/trauma (> 65
disease states Pathophysiology ... 2000-100,000/µL; neutrophil ... 2000-100,000/µL; neutrophil ... Intracellular (leukocyte ... protein, ESR, leukocytosis
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