7 results
Step by Step Algorithmic Approach to Pediatric Fever

Age < 21 days old (or 28 days for
Algorithmic Approach to Pediatric ... sensitivity) Leukocytes ... in the urine Procalcitonin ... ANC > 10000 #Pediatrics
Lower Urinary Tract Infection: Pathogenesis and Clinical Findings

- Predisposing Factors:  Immunocompromised state, diabetes, elderly, female
urethra), stagnant urine ... systems, or stagnant urine ... Tenderness - Urine ... (+) Nitrites, Leukocyte ... UrinaryTractInfection #LUTI #Pathophysiology
“Step by Step” – the new kid on the block – aims to risk stratify this
>21 days - No leukocytes ... in urine - Procalcitonin ... Diagnosis #Management #Pediatrics
Gout: Pathogenesis and Clinical Findings
 - Conditions of rapid cell turnover: hemolysis, psoriasis, lymphoproliferative disorders
 -
for excretion in urine ... cascade results in leukocyte ... Hyperuricemia #Pathophysiology
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
peripheral blood leukocytes ... on the left Myeloblast ... CBC #hematology #pathophysiology
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings
Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
non-arousable, decr urine ... #21HydroxylaseDeficiency #21OHD #pathophysiology ... endocrinology #peds #pediatrics
Alkaptonuria (Black Urine Disease)
Urine turns dark when left standing due to oxidation of homogentisic acid 
Clinical
Alkaptonuria (Black Urine ... Disease) Urine ... BlackUrine #Peds #Pediatrics ... #Diagnosis #Pathophysiology