14 results
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
• Blasts > 10% leukocytes ... Neutrophils • Immature/Myeloblasts ... develop leukostasis syndrome ... • Tumor lysis syndrome ... Leukemia #Hematology #Oncology
Tumor Lysis Syndrome - Workup and Management

Initial workup: BMP, Serum uric acid, LDH, Urine output, Consider
Tumor Lysis Syndrome ... uric acid, LDH, Urine ... of the above Treatment ... of Clinical TLS ... diagnosis #management #oncology
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
of Tumor Lysis Syndrome ... (TLS) and Treatment ... Calcium ≤ 7.0 mg/dL Clinical ... #TumorLysis #Syndrome ... diagnosis #management #oncology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
immunophenotype Clinical ... transformation) Treatment ... AIHA, PRCA) • Treatment ... chlorambucil) 2) Purine ... Lymphocytic #Leukemia #oncology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
- Compartment syndrome ... Dermatomyositis Clinical ... Weakness - Dark urine ... or compartment syndrome ... hour with goal urine
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Constitutional Syndromes ... Aplastic Anemia Clinical ... Constitutional Syndromes ... aplastic anemia Treatment ... Aplastic #Anemia #oncology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... microglobulin Treatment ... • Richter’s Syndrome ... leukemia • Sezary syndrome ... diagnosis #workup #oncology
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
status and low urine ... & Dry) is the treatment ... acute coronary syndrome ... & Dry” is the treatment ... management #cardiology #treatment
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
., urine, sweat) ... of lactate as a clinical ... perfusion - shock->treatments ... before beginning treatment ... - Compartment syndrome
Clarkson’s Disease - Capillary leak syndrome
Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
Capillary leak syndrome ... Relapsing-remitting course +++ Clinical ... edema, compartment syndrome ... hypoalbuminemia with no urine ... Capillary #leak #syndrome