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diagnosis causes generalized pruritus secondary systemic aplastic clinical cutaneous leukemia macrocytic macrocytosis management manifestations mds monoclonal myelodysplasia paraproteinemias primary syndrome
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Diagnosis Algorithm ... Dysplastic • Myelodysplastic ... Syndromes Macrocytosis ... #Macrocytosis #elevatedMCV ... #Causes #Hematology
Cutaneous manifestations associated with myelodysplastic syndrome • Myeloid hemopathy with the most frequent skin lesions (20%)
most frequent skin ... #syndrome #differential ... #diagnosis #dermatology ... #oncology #clinical ... #skin
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
just beneath the skin ... hematopoiesis cell lineages—erythrocytic ... single-lineage dysplasia ... blood count with differential ... #hematology #oncology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Diagnosis Algorithm ... renal failure/uremia ... Throbocythemia • Myelodisplastic ... syndrome Psychiatric ... #generalized #dermatology
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Pruritus - No Primary Skin ... renal failure/uremia ... Throbocythemia • Myelodisplastic ... syndrome Psychiatric ... #generalized #dermatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Headaches • Pale skin ... • Hypocellular myelodysplastic ... syndrome (MDS) ... #oncology #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Neutrophils • Immature/Myeloblasts ... - infiltrates (anemia ... CLL -> Invade Skin ... #Leukemia #Hematology ... #Oncology #Diagnosis
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Alpha & Mu) Skin ... (-) hemolytic anemia ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
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