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causes neurology algorithm seizures alkalosis encephalopathy epilepticus gitelman hyperkalemia hypokalemia intercellularshift pathophysiology posterior pres reversible status treatment urinary urine weakness
Metabolic Alkalosis - Urinary Chloride Algorithm Cl- responsive metabolic alkalosis • Kidney loss of Cl-
alkalosis • Normal/low ... , Gitelman syndrome ... urine #Algorithm #nephrology ... #differential # ... diagnosis
Causes of Seizures - Differential Diagnosis Algorithm Unprovoked - Epilepsy: • Focal: Simple, Complex • Generalized: Absence,
Diagnosis Algorithm ... vasoconstriction syndrome ... Neurocysticercosis, PML • Metabolic ... Hyperglycemia, Hyponatremia ... #Causes #neurology
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
alkalosis • Normal or low ... ratio 0.5%) Differential ... • Seizures • Rhabdomyolysis ... #diagnosis #nephrology ... #management #pathophysiology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Differential Diagnosis ... Heat stroke - Metabolic ... Hyperuricemia • Hyponatremia ... Diagnosis #Management ... causes #treatment #nephrology
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
Weakness - Differential ... Diagnosis Framework ... nervous system: Brain ... Lyme myositis • Rhabdomyolysis ... #Diagnosis #neurology
Causes of Hyperkalemia - Intercellular Shift - Differential Diagnosis Algorithm Transcellular Shift - Appropriate renal excretion (GFR,
, TTKG, distal flow ... Non-Anion Gap Metabolic ... Tumor Lysis Syndrome ... , rhabdomyolysis ... IntercellularShift #Nephrology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
parietal lobes of the brain ... Reversible course Differential ... Drug toxicity, Metabolic ... #diagnosis #management ... #neurology
Causes of Status Epilepticus in Adults METABOLIC DISTURBANCES Hepatic encephalopathy Hypocalcemia Hypoglycemia or hyperglycemia Hyponatremia Uremia INFECTIOUS PROCESSES Central nervous system abscess Encephalitis Meningitis WITHDRAWAL SYNDROMES Alcohol Antiepileptic drugs Baclofen Barbiturates Benzodiazepines CENTRAL
Epilepticus in Adults METABOLIC ... hyperglycemia Hyponatremia ... Meningitis WITHDRAWAL SYNDROMES ... malformations Brain ... #diagnosis #causes
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