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management chronic cll leukemia lymphocytic workup anemia aplastic apml calcium cell classification cppd deposition differentiation disease gout hemeonc hodgkins lymphoma
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... if high risk if WBC ... QD until normal WBC ... #management #hematology ... #oncology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
minimal tumor burden Diagnosis ... Vmphocytosis on routine CBC ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc ... #diagnosis #management
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Pancytopenia: • ↓ RBC ... • ↓ WBC • ↓ ... aplastic anemia Treatment ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
phenomenon CLL Diagnosis ... Lymphocytosis on CBC ... microglobulin Treatment ... #workup #oncology ... #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
platelets - WBC ... lymph node biopsy (diagnostic ... Hodgkin Lymphoma Treatment ... classification #hematology ... #oncology #management
Gout - Diagnosis and Management Summary 3 Conditions for Gout to Manifest: 1. Hyperuricemia 2. Monosodium urate deposition in
Gout - Diagnosis ... Fluid Testing: • WBCs ... not possible • Ultrasound ... • Acute gout treatment ... #rheumatology
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD) Pathophysiology: Pyrophosphate produced by chondrocytes likely precipitates with calcium to
Synovial Fluid: • WBCs ... culture used to diagnose ... Acute Pseudogout: Treatment ... Deposition #Disease #Rheumatology ... #diagnosis #management
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
Diagnosis? ... • CBC + diff • ... Bone marrow Treatment ... #Plasmacytoma #Oncology ... #Hematology
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