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differential oncology dermatology generalized secondary systemic anemia chronic cll lymphocytic management primary thrombocytopenia workup
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Megakaryopoiesis • Aplastic ... Leukemia, Tumour ... Non-lmmune: • HELLP Syndrome ... #Algorithm #Causes ... #Hematology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Pruritus - Generalized ... and Primary Causes ... • Lymphoma • Leukemia ... Myelodisplastic syndrome ... #Algorithm #causes
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Anemia Clinical ... and petechiae Causes ... virus (EBV) • Leukemia ... • ↓ WBC • ↓ ... Anemia #oncology #hematology
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Pruritus - No Primary ... Hyperthyroidism CBC ... • Lymphoma • Leukemia ... Myelodisplastic syndrome ... #Algorithm #causes
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
sweats, bleeding • Pruritis ... Neutrophils • Immature/Myeloblasts ... • Tumor lysis syndrome ... #Hematology #Oncology ... #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... Lymphocytosis on CBC ... Pure red cell aplasia ... #diagnosis #workup ... #oncology #hematology
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