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White Blood Cell Maturation Chart

#Pathology #WBC #Maturation #Lineage #Chart #Leukocyte #Myeloid #Myeloblast #Lymphocyte
#Pathology #WBC ... Leukocyte #Myeloid #Myeloblast
Evaluation of Leukocytosis:
The term 'leukocyte' applies to any cells within the myeloblast, monoblast, & lymphoid lineages.
Include
cells within the myeloblast ... white blood cell (WBC ... Mature WBC: 80- ... LEUCOCYTOSIS WBC ... Transient increase in WBC
Urine Microscopy and Casts - Image Atlas Key

- Squamous Epithelial Casts
- Transitional Epithelial Cells
- Renal Tubular
Hyaline Cast - WBCs ... Granular Casts - WBC ... Cast - RBC Cast
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
on the left Myeloblast ... Even with normal WBC ... relative to both WBC ... 21% had normal WBC ... diagnosis #neutrophil #WBC
Urinalysis Interpretation (UA)

Bacteria, Leukocyte esterase, WBC, Nitrite, RBC, Epithelial 
cells, pH

#Diagnosis #Urinalysis #Interpretation #Analysis
Leukocyte esterase, WBC ... , Nitrite, RBC,
Blood Product Components, Contents, Volume and Shelf Life

Whole blood (autologous or directed donations) - RBC and
WBC and platelets ... Hct of 70-80% - RBC ... X 1010); some WBC ... plasma, a few RBC ... X 1011); some WBC
Algorithm and Differential Diagnosis of Macroscopic Hematuria
Important Historical Elements:
- Painless: suggests malignancy
- Painful: suggests calculi/infection
- Urinalysis:
dysmorphic RBC’s, RBC ... /WBC casts, proteinuria
Arthrocentesis - Synovial Fluid Analysis
Normal < 150 WBC, Colorless/Straw color, High Viscosity
Noninflammatory < 3,000 WBC, Straw/yellow
Analysis Normal < 150 WBC ... Noninflammatory < 3,000 WBC ... Inflammatory > 3,000 WBC ... purulent) > 50,000 WBC ... Viscosity Hemorrhagic WBC
Here are very large, immature myeloblasts with many nucleoli. A distincitve feature of these blasts is
large, immature myeloblasts
Approach to Leukocytosis - Differential Diagnosis Algorithm

Features of hematologic malignancy:
 • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
platelets, persistent WBC ... Algorithm #hematology #WBC