24 results
Idiopathic Thrombocytopenic Purpura 
Clinical:
 • Gingival 
 • Menorrhagia 
 • GI bleeding 
 • Intracranial
Intracranial hemorrhage Management ... children) • Platelets ... extremely low platelet ... #Purpura #Thrombocytopenia ... #Diagnosis #Overview
Inherited Qualitative Platelet Defects
Bernard-Soulier Syndrome
 • Defect of adhesion due to a lack of GP Ib/IX/V
, Large platelets ... without platelet ... MYH9-Related Disorder ... comparison #table #differential ... #diagnosis #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... RBC's secondary to platelet ... • Platelet defects ... : Platelet Defects ... Diagnosis #hematology
Platelet disorders and Aggregometry
Glanzmann Thrombasthenia
 • Defective aggregation to all agonists except ristocetin
 • Normal platelet,
Platelet disorders ... Gplb receptor • Thrombcytopenia ... #disorders #hematology ... #hemepath #differential ... #diagnosis #Aggregometry
Causes of Purpura - Differential Diagnosis
Disruption in Vascular Integrity: 
 • Trauma, Infection, Vasculitis, Drug induced
- Differential ... Diagnosis Disruption ... collagen vascular disorders ... Primary hemostasis: Thrombocytopenia ... , Platelet dysfunction
Causes of Purpura or Easy Bruising in Children

Platelet count reduced, i.e. thrombocytopenia
 - Increased platelet destruction
in Children Platelet ... - Increased platelet ... Hypersplenism - Impaired platelet ... Drug-induced Platelet ... count normal - Platelet
Thrombocytopenia - Differential Diagnosis Algorithm

Decreased production:
 • Bone marrow suppression
 • Bone marrow failure
 • Bone
Thrombocytopenia ... - Differential ... Diagnosis Algorithm ... Connective tissue disorders ... #hematology #platelets
Treatment of Thrombotic Thrombocytopenic Purpura (TTP)
Diagnosis of TTP:
 • Rare and severe, ADAMTS13 deficiency
 • Autoimmune
Thrombocytopenic ... secondary TMA), Platelets ... Contraindication to platelets ... #Purpura #management ... #hematology
Thrombocytopenia - Differential Diagnosis and Management Framework for Low Platelets

#Thrombocytopenia #Differential #Diagnosis #Management #hematology #platelets
Thrombocytopenia ... Diagnosis and Management ... Framework for Low Platelets ... Diagnosis #Management ... #hematology #platelets
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
and Platelet Disorders ... - Differential ... Diagnosis and Workup ... History: - Prior platelet ... #Platelet #Disorders